Here is a statement from ABC Family Executive Karey Burke regarding the cancellation:
We are proud of the milestones Melissa & Joey has achieved, being the network’s first sitcom to reach 100 episodes and the network’s first comedy to win a People’s Choice Award. Now that the kids are grown and Mel and Joe have married and are looking toward starting a family, it seemed like a natural time to bring the series to a close. We are grateful to Melissa Joan Hart and Joey Lawrence, and the whole cast and crew who worked so hard on this successful show.
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